Copenhagen Bioscience PhD Programme

Fully-funded four year PhD programme in an international scientific environment

Supervisors 2018

These potential supervisors are offering projects for students starting in 2018.

The research topics listed below give an idea of the research in each supervisor’s lab. Follow the links to the lab webpages to find out more. Each Copenhagen Bioscience PhD programme applicant is expected to discuss and justify the research topics they are interested in as part of their application. This is an expression of interest only, and does not commit the applicant to any particular group.

Candidates joining the Copenhagen Bioscience PhD programme select three labs for short rotation projects after starting the programme, then make an agreement with one of the rotation supervisors to host their long-term (PhD) project. The ultimate PhD project is developed in collaboration between the supervisor and student, according to their mutual interests.

DanStem  |  CPR  |  CBMR | CFB


Center for Stem Cell Biology (DanStem)

Josh BrickmanSelf-organizing transcriptional networks mediating pluripotency and differentiation

Anne Grapin-Botton – Single cell investigation of organ formation in human stem cell and mouse models

Elisabetta FerrettiDissecting mechanisms of lineage choice and mesoderm specification 

Kristian HelinTargeting epigenetic enzymes in cancer

Agnete KirkebyModelling human brain development in 3D with stem cells

Elke OberProgenitor cell dynamics and potency in zebrafish liver organogenesis and regeneration

Ole William PetersenThe cellular origin of human breast cancer

Bo PorseEpigenetic control in normal and malignant hematopoiesis

Jakub SedzinskiFrom single molecules to forces. A quantitative understanding of epithelial homeostasis at the sub-cellular, cellular and tissue level

Henrik SembIntegration of morphogenesis and cell differentiation during organogenesis

Palle Serup – How signals and transcription factors coordinate cell fate choices


Center for Protein Research (CPR)

Søren BrunakUnderstanding the network biology of multi-morbidity patients with more than one disease

Chuna Ram ChoudharySystems-wide analysis of cell signaling networks

Julien DuxinMechanisms of replication-coupled DNA repair

Lars Juhl JensenNetwork biology: large-scale biomedical data and text mining

Jiri LukasMolecular pathways that guard integrity of human genomes against endogenous DNA damage

Niels MailandFunctional characterization of DNA damage signaling pathways

Matthias Mann – Patient stratification by their plasma proteomes

Guillermo MontoyaStructural cell biology of genome editing protein-DNA complexes

Michael Lund NielsenCharacterizing post-translational modifications by quantitative proteomics

Jakob NilssonProtein phosphatases in cellular signaling

Jesper OlsenGlobal analysis of disease signaling pathways by quantitative phosphoproteomics

Nicholas Taylor* – Revealing the mechanisms of biomolecular machines using high-resolution cryo-electron microscopy


Center for Basic Metabolic Research (CBMR)

Ken ArnoldPublic Engagement with Metabolic Research through Exhibitions: Developing Theoretical and Practical Frameworks for Collection and Display

Manimozhiyan ArumugamSystems biology and bioinformatics for studying human microbiome in health and disease

Romain BarrèsTo identify the critical epigenetic nodes controlling the gene expression response to exercise in human muscle

Christoffer ClemmensenCentral control of energy metabolism – role of the cholinergic system

Brice EmanuelliExploring the Molecular Mechanisms Controlling Insulin Action and Metabolic Functions

Zach Gerhart-HinesControl of brown and beige adipose metabolism by the body’s clock

Matthew GillumHormonal remote control of pleasure-seeking by the liver

Niels GrarupPhysiological impact of the human genome in metabolism

Torben Hansen(1) Studies of genetics of metabolism in population isolates; (2) The role of the gut-liver axis in development of NAFLD

Bolette HartmannInvestigating the link between gut hormones and bone remodeling

Birgitte HolstHypothalamic sensing of nutritional status and regulation of appetite

Jens Juul HolstTranslational aspects of obesity and diabetes development and treatment

Tuomas KilpeläinenInterplay between genetic and lifestyle factors in metabolic health

Filip KnopThe integrative role of the gut in human glucose metabolism – physiologic, pathophysiologic and pharmocologic implications

Tune H. PersUncovering neuronal cell types controlling obesity using single-cell transcriptomics

Thue SchwartzMetabolites and metabolite receptors as signaling drivers of metabolic inflammation in obesity and diabetes

Thorkild Ingvor Arrild Sørensen(1) Gene-environment interactions in the development of the obesity epidemic; (2) Roles of genes predisposing to adiposity in body weight changes over time

Signe TorekovPotential synergistic effects of GLP-1 analogues and physical exercise on immuno-metabolic health

Jonas Thue Treebak – Role of hepatic NAD salvage capacity for development of liver fibrosis and NASH

Louise WhiteleyMedia Representation of Metabolic Research and the Relationship between Science and Society


Center for Biosustainability (CFB)

Irina Borodina – Synthetic biology of yeast for bio-based chemicals

Markus HerrgardData-driven engineering of cell factories

Michael Krogh JensenSynthetic biology tools and refactored natural products biosynthesis in yeast

Helene Faustrup KildegaardGenome engineering of CHO cells towards improved therapeutic protein production

Ivan Mijakovic – Using evolutionary age to characterize genes of unknown function

Solange I. MussattoAdaptive laboratory evolution of yeasts for lignocellulosic hydrolysate bioconversion

Alex Toftgaard NielsenOptimizing the folding and secretion of industrially relevant proteins in bacteria

Lars NielsenModelling complex pathway kinetics using Bayesian sampling

Pablo Iván NikelEngineering the biochemical landscape of environmental bacteria

Morten NørholmMicrobial evolution and synthetic biology

Morten SommerEngineering advanced microbiome therapeutics

Nikolaus SonnenscheinFully automatic cell factory engineering: bridging the gap between model predictions and strain construction

Tilmann WeberEngineering antibiotics production in actinomycetes

Ditte Hededam Welner* – Engineering and stabilization of glycosyltransferase enzymes for industrial applications

 

*New Group Leader – will be present at the Center by the time of the interview visit in March

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