Copenhagen Bioscience PhD Programme

Fully-funded four year PhD programme in an international scientific environment

Supervisors 2020

Supervisors

These potential supervisors are offering projects for students starting in 2020.

The research topics listed below give an idea of the research in each supervisor’s lab. Follow the links to their lab webpages and read their publications to find out more.

The following supervisors are also part of CPH Bioscience PhD but are not offering long-term projects for students starting in 2020: Elisabetta Ferretti, Elke Ober, Julien Duxin, Michael Lund Nielsen, Juleen Zierath.

Applicants to CPH Bioscience PhD must explain their research interests in their application, but are not committed to any particular group until after joining the programme.

New pre-doc students must complete three short rotation projects in different labs, then make an agreement with one of their rotation supervisors to host their long-term (PhD) project. The ultimate PhD project is developed in collaboration between the supervisor and student, according to their mutual interests.

Each student applies to and is initially recruited by one of the four Centers. However, it is possible to do rotation projects at other Centers; and students may apply to change Center after completing their rotation projects.

DanStem  |  CPR  |  CBMR | CFB


Center for Stem Cell Biology (DanStem)

Mariaceleste Aragona (started 1 Sept 2020) – Tissue architecture: addressing stem cell dynamics in epithelia

Luis Arnes PerezTranscriptional regulation of cellular identity in development and cancer. Understanding the “dark-side“ of the genome.

Josh Brickman – Transcriptional basis for stem/progenitor cell potency

Kim Bak Jensen – Regulatory mechanisms controlling stem cell fate during development, homeostasis and disease

Bo PorseEpigenetic control in normal and malignant hematopoiesis

Jakub Sedzinski – How to build a tissue? Combining cell developmental biology, biophysics, and systems biology approaches to understand morphogenesis.

Henrik Semb – Fate determination of organ progenitors within a constantly remodeling niche

Palle Serup – Control of cell fate in fetal pancreas and organoids by oscillating Notch signalling

Jan Żylicz Epigenetic and metabolic regulation of early development


Center for Protein Research (CPR)

Søren BrunakUnderstanding the network biology of multi-morbidity patients with more than one disease

Chuna ChoudharySystems-wide analysis of cell signaling networks

Anja GrothMolecular mechanisms in chromatin replication and epigenome maintenance that guide cell fate

Lars Juhl Jensen – Network biology: large-scale biomedical data and text mining

Jiri Lukas – Genome integrity maintenance in the context of cellular metabolism and 3D nuclear organization

Niels MailandCharting genome maintenance pathways using CRISPR screening

Matthias Mann – Mass spectrometry based proteomics for clinical applications in metabolic diseases and cancer

Guillermo Montoya – cryoEM of protein complexes involved in genome instability 

Jakob NilssonProtein phosphatases in cellular signaling

Jesper V. OlsenGlobal analysis of disease signaling pathways by quantitative phosphoproteomics

Simon Rasmussen – Deep learning for human multi-omics variation data in health and disease

Nicholas Taylor – Revealing the mechanisms of biomolecular machines using high-resolution cryo-electron microscopy


Center for Basic Metabolic Research (CBMR)

Ken Arnold(1) History of museums; (2) Relation of arts & sciences; (3) Public engagement with medicine & sciences

Manimozhiyan Arumugam – Gut microbial metabolites modulating host metabolism

Romain Barrès – Epigenetic gametic inheritance in metabolic diseases

Adam BencardCultural, philosophical and historical contexts for metabolic science, and the complex meetings between science and the public

Christoffer Clemmensen – Neuroendocrine regulation of satiety: Transforming molecular insights into therapeutic strategies

Atul DeshmukhProtein dynamics in response to diet and physical exercise using mass spectrometry-based proteomics

Brice Emanuelli – Mechanisms linking adipose tissue functions and plasticity to metabolic health

Thomas Frimurer – Molecular modeling and structure-based drug design

Zach Gerhart-Hines – Environmental control of adipose tissue metabolism and systemic energy homeostasis

Matthew GillumRemote control of appetite and hedonism by the liver

Niels GrarupPhysiological impact of the human genome in metabolism

Torben HansenMulti-omics profiling to understand the molecular etiology of childhood obesity and to improve preventive and treatment strategies

Tuomas Kilpeläinen – Translating human genetic variation into new understanding of metabolic diseases

Thomas MoritzUnderstanding the function of metabolites using quantitative metabolomics and dynamic metabolomics

Tune H. PersUncovering neuronal cell types controlling obesity using single-cell transcriptomics

Kei SakamotoUncovering molecular and cellular signaling mechanisms that control metabolic functions

Camilla Charlotte SchéeleBrown fat communication with the central nervous system

Thue W. SchwartzSignaling metabolites and their specific receptors as regulators of endocrine and metabolic function and drivers of metabolic inflammation in obesity and diabetes

Jonas Thue Treebak – Defining the role of NAD+ generating/consuming pathways for maintaining metabolic health and tissue function

Louise Whiteley – (1) Media representations of metabolic research; (2) Cultural perspectives on mind-gut-microbiome connections; (3) Science-society relations


Center for Biosustainability (CFB)

Irina Borodina – Metabolic Engineering of yeast for bio-based chemicals

Michael Krogh Jensen – Synthetic biology of the model eukaryote baker’s yeast

Douglas McCloskeyGeneration and analysis of Big–Omics Data using automation (i.e., liquid handling robots), analytics (e.g., LC-MS/MS), machine learning (e.g., deep learning), and biochemical modeling (e.g., metabolic flux analysis) for bioengineering applications

Ivan Mijakovic – Metabolic engineering of a CO2 fixation pathway in Bacillus subtilis – cell factories to counter climate change

Alex Toftgaard NielsenProduction of biochemicals using bacterial cell factories

Lars Keld NielsenData-driven design of cell factory

Pablo I. NikelData-driven engineering of microbial cell factories towards new-to-Nature bioproducts

Morten NørholmMicrobial evolution and synthetic biology

Morten SommerEngineering advanced microbiome therapeutics

Tilmann Weber – Next generation genome mining for antibiotics and other specialized metabolites

Ditte Hededam Welner – Enzyme engineering and structural biology for biosustainability