These potential supervisors are offering projects for students starting in 2020.
The research topics listed below give an idea of the research in each supervisor’s lab. Follow the links to their lab webpages and read their publications to find out more.
The following supervisors are also part of CPH Bioscience PhD but are not offering long-term projects for students starting in 2020: Elisabetta Ferretti, Elke Ober, Julien Duxin, Michael Lund Nielsen, Juleen Zierath.
Applicants to CPH Bioscience PhD must explain their research interests in their application, but are not committed to any particular group until after joining the programme.
New pre-doc students must complete three short rotation projects in different labs, then make an agreement with one of their rotation supervisors to host their long-term (PhD) project. The ultimate PhD project is developed in collaboration between the supervisor and student, according to their mutual interests.
Each student applies to and is initially recruited by one of the four Centers. However, it is possible to do rotation projects at other Centers; and students may apply to change Center after completing their rotation projects.
Center for Stem Cell Biology (DanStem)
Mariaceleste Aragona (new – to start 1 Sept 2020) – Tissue architecture: addressing stem cell dynamics in epithelia
Luis Arnes Perez – Transcriptional regulation of cellular identity in development and cancer. Understanding the “dark-side“ of the genome.
Josh Brickman – Transcriptional basis for stem/progenitor cell potency
Kim Bak Jensen – Regulatory mechanisms controlling stem cell fate during development, homeostasis and disease
Bo Porse – Epigenetic control in normal and malignant hematopoiesis
Jakub Sedzinski – How to build a tissue? Combining cell developmental biology, biophysics, and systems biology approaches to understand morphogenesis.
Henrik Semb – Fate determination of organ progenitors within a constantly remodeling niche
Palle Serup – Control of cell fate in fetal pancreas and organoids by oscillating Notch signalling
Jan Żylicz – Epigenetic and metabolic regulation of early development
Center for Protein Research (CPR)
Søren Brunak – Understanding the network biology of multi-morbidity patients with more than one disease
Chuna Choudhary – Systems-wide analysis of cell signaling networks
Anja Groth – Molecular mechanisms in chromatin replication and epigenome maintenance that guide cell fate
Lars Juhl Jensen – Network biology: large-scale biomedical data and text mining
Jiri Lukas – Genome integrity maintenance in the context of cellular metabolism and 3D nuclear organization
Niels Mailand – Charting genome maintenance pathways using CRISPR screening
Matthias Mann – Mass spectrometry based proteomics for clinical applications in metabolic diseases and cancer
Guillermo Montoya – cryoEM of protein complexes involved in genome instability
Jakob Nilsson – Protein phosphatases in cellular signaling
Jesper V. Olsen – Global analysis of disease signaling pathways by quantitative phosphoproteomics
Simon Rasmussen – Deep learning for human multi-omics variation data in health and disease
Nicholas Taylor – Revealing the mechanisms of biomolecular machines using high-resolution cryo-electron microscopy
Center for Basic Metabolic Research (CBMR)
Ken Arnold – (1) History of museums; (2) Relation of arts & sciences; (3) Public engagement with medicine & sciences
Manimozhiyan Arumugam – Gut microbial metabolites modulating host metabolism
Romain Barrès – Epigenetic gametic inheritance in metabolic diseases
Adam Bencard – Cultural, philosophical and historical contexts for metabolic science, and the complex meetings between science and the public
Christoffer Clemmensen – Neuroendocrine regulation of satiety: Transforming molecular insights into therapeutic strategies
Atul Deshmukh – Protein dynamics in response to diet and physical exercise using mass spectrometry-based proteomics
Brice Emanuelli – Mechanisms linking adipose tissue functions and plasticity to metabolic health
Thomas Frimurer – Molecular modeling and structure-based drug design
Zach Gerhart-Hines – Environmental control of adipose tissue metabolism and systemic energy homeostasis
Matthew Gillum – Remote control of appetite and hedonism by the liver
Niels Grarup – Physiological impact of the human genome in metabolism
Torben Hansen – Multi-omics profiling to understand the molecular etiology of childhood obesity and to improve preventive and treatment strategies
Tuomas Kilpeläinen – Translating human genetic variation into new understanding of metabolic diseases
Thomas Moritz – Understanding the function of metabolites using quantitative metabolomics and dynamic metabolomics
Tune H. Pers – Uncovering neuronal cell types controlling obesity using single-cell transcriptomics
Kei Sakamoto – Uncovering molecular and cellular signaling mechanisms that control metabolic functions
Camilla Charlotte Schéele – Brown fat communication with the central nervous system
Thue W. Schwartz – Signaling metabolites and their specific receptors as regulators of endocrine and metabolic function and drivers of metabolic inflammation in obesity and diabetes
Jonas Thue Treebak – Defining the role of NAD+ generating/consuming pathways for maintaining metabolic health and tissue function
Louise Whiteley – (1) Media representations of metabolic research; (2) Cultural perspectives on mind-gut-microbiome connections; (3) Science-society relations
Center for Biosustainability (CFB)
Irina Borodina – Metabolic Engineering of yeast for bio-based chemicals
Michael Krogh Jensen – Synthetic biology of the model eukaryote baker’s yeast
Douglas McCloskey – Generation and analysis of Big–Omics Data using automation (i.e., liquid handling robots), analytics (e.g., LC-MS/MS), machine learning (e.g., deep learning), and biochemical modeling (e.g., metabolic flux analysis) for bioengineering applications
Ivan Mijakovic – Metabolic engineering of a CO2 fixation pathway in Bacillus subtilis – cell factories to counter climate change
Solange I. Mussatto – Strain improvement for application in sustainable and advanced fermentation processes
Alex Toftgaard Nielsen – Production of biochemicals using bacterial cell factories
Lars Keld Nielsen – Data-driven design of cell factory
Pablo I. Nikel – Data-driven engineering of microbial cell factories towards new-to-Nature bioproducts
Morten Nørholm – Microbial evolution and synthetic biology
Morten Sommer – Engineering advanced microbiome therapeutics
Tilmann Weber – Next generation genome mining for antibiotics and other specialized metabolites
Ditte Hededam Welner – Enzyme engineering and structural biology for biosustainability